517/2000 With the global population ageing problem increasing, in the orthopaedic field, osteonecrosis of the femoral head, severe trauma, bone tumor, osteomyelitis and other causes of bone problems will be hindering the elderly to enjoy a happy life of the prime culprit. Among the nearly 100 million patients with bone tissue in our country, there are about 70 million patients with osteoporosis, 10 million patients with bone defect and 8 million patients with stump. The population of our country accounts for about 20% of the world, the biological material product is less than 10% , the global hard tissue repair market needs nearly 200 billion yuan. There is a huge space for the development of artificial bone materials for bone tissue repair. The development of ideal artificial bone materials is an important subject in the fields of medicine and materials science. CR200D regenerated bone 3D intelligent manufacturing center is designed to solve the current problems of artificial bone production.The application of 3D molding biotechnology in the field of biomedicine and health has become one of the most widely industrialized fields. It takes the three-dimensional model of biology as the“Drawing”, assembles the special“Bio-ink”, and finally produces the artificial organ and the bio-medical product. In 2018, the domestic 3d-printed renewable artificial bone technology has passed the animal test, physical and chemical test, clinical test, all verified the safety and effectiveness of the product. The 2023“Absorbable regenerated bone” Gaiabon from Shenzhen Lixin Science Co. , Ltd. has been approved for listing by FDA 510(K) . CR100D regenerated bone 3D intelligent manufacturing center consists of whole machine control system, 3D holographic scanning reconstruction system, feeding system, polymer printer, bio-material printer, sterilization system and packaging system. The control system of the whole machine is used for the operation of the whole intelligent building center, and the 3D holographic scanning reconstruction system is used for the reconstruction of the model of the defective bone, the feeding system is used to configure the printer, the polymer printer is used to construct the bone structure, the biomass printer is used to fill the biomass, and the sterilization system is used to sterilize the finished product, the packaging system is used for the protection and transportation of the final product.The CR200D intelligent manufacturing center defines a new type of medical preparation product with a completely new sealed appearance. Unlike traditional 3D printing equipment, it adopts a composite printing function with multi-material and double-position simultaneously, the outer shell of the whole machine is made of anti-bacterial composite plastic, which not only assures the requirement of medical hygiene but also gives consideration to the technological requirement of affinity form. Soft lines and pleasant appearance of the design swept away the cold feeling of the equipment, combined with functional lighting greatly enhance the overall atmosphere of the medical work space. Medical-grade assembly process requirements, incorporating ergonomic design standards, the CR200D intelligent manufacturing center emphasizes and highlights the appearance characteristics of medical equipment while taking into account the ease of use, aesthetics, observability and convenience of the equipment, make the equipment operation, maintenance, disassembly more practical and convenient, clear unit identification and status indication, let the operator and the audience quickly identify the status and process of the equipment, in order to improve the work efficiency and comfort of medical staff and improve the accuracy and safety of medical equipment, different areas are divided into different shapes and colors.An analysis of the orthopaedic strategies of world-renowned medical device companies reveals that surgical robotics and 3D printing are both key placement directions. General Motors is investing $1.5 billion in 3D printing and additive manufacturing, and Johnson & Johnson is working closely with leading companies in the field of 3D printed orthopaedic implants. With the maturity of 3D printing technology, the medical field is expected to form a mass customization market. In 2016, the global 3D printing orthopaedic market was valued at US $500 million and is expected to reach US $3.441 billion by the end of 2025. And orthopaedic implants are one of the first medical applications where 3D printing technology has been commercialized, allowing for real customization to patients' sizes and needs to improve medical capabilities. A significant improvement over existing methods is that custom-printed bone can rapidly induce bone regeneration and growth. The birth of any new technology and product will leave a deep footprint in the development of human civilization. We hope that at the moment when many countries are technically blockading our country internationally, with the growth of global market demand, in order to benefit mankind and develop our country's medical cause, we all need to exert ourselves in this subdivided field, so as to leave a strong mark belonging to our China.CR200D intelligent manufacturing center uses medical plastic, environmental protection steel, electrical components, the machine itself does not produce pollutants, the use of unmanned production, equipment security has a good guarantee. The main raw materials used in the preparation are hydroxylapatite calcium sulfate, bioceramics, collagen, bioactive glass and other synthetic polymers. When the machine is running, it adopts the same operation mode as CT, using terminal computer and data center to control the equipment in the control room, reducing human intervention, making the equipment more convenient, reliable and accurate.